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PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Selected by 29 December 2025

Vibha SINGH

Cell Biology

Loss of MGST1 during fibroblast differentiation enhances vulnerability to oxidative stress in human heart failure

Mohamad Youness, Onne A.H.O. Ronda, Ankit Pradhan, et al.

Selected by 15 December 2025

Jeny Jose

Immunology

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Selected by 09 December 2025

Inês Caiado

Immunology

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Selected by 01 December 2025

Jawdat Sandakly

Developmental Biology

Gut microbial composition modulates food-specific CD4+ T cells in food allergy

Alexa R Weingarden, Flannery S Dahlberg, Caroline N Broude, et al.

Selected by 28 November 2025

Mitchell Sarmie, Serena Restori

Immunology

Actin Counters Geometry to Guide Plant cell Division

Camila Goldy, Samantha Moulin, Yutaro Shimizu, et al.

Selected by 26 November 2025

Jeny Jose

Cell Biology

Dissecting Gene Regulatory Networks Governing Human Cortical cell fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

Neuroscience

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Neuroscience

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Selected by 05 August 2025

Justin Gutkowski

Developmental Biology

Leveraging autophagy and pyrimidine metabolism to target pancreatic cancer

Suzanne Dufresne, Ramya S Kuna, Kristiana Wong, et al.

Selected by 24 July 2025

Hannah Pletcher

Cancer Biology

Succinate Dehydrogenase loss causes cascading metabolic effects that impair pyrimidine biosynthesis

Madeleine L. Hart, Kristian Davidsen, Serwah Danquah, et al.

Selected by 26 May 2025

Hannah Pletcher

Cancer Biology

A conserved differentiation program facilitates inhibitory neuron production in the developing mouse and human cerebellum

Jens Bager Christensen, Alex P.A. Donovan, Marzieh Moradi, et al.

Selected by 15 May 2025

Jethro Lundie-Brown

Developmental Biology