Direct cell-to-cell transmission of retrotransposons

An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer

Wenyan Xie, Xin Yu, Qingxin Yang, et al.

Selected by 20 May 2025

Roberto Amadio

Cortical astrocyte activation triggers meningeal nociception and migraine-like pain

Dara Bree, Jun Zhao, Jennifer Stratton, et al.

Vanessa Ehlers

A prophage-encoded anti-phage defense system that prevents phage DNA packaging by targeting the terminase complex

Gil Azulay, Nadejda Sigal, Keren Tzohar Rabinovich, et al.

Briana Guzman et al.

tRNA synthetase activity is required for stress granule and P-body assembly

Max Baymiller, Noah S. Helton, Benjamin Dodd, et al.

Mohammed JALLOH

Early resident NK cell response to local HIV infection in lymphoid tissue

David Perea, Alba Gonzalez, Nerea Sanchez-Gaona, et al.

Sukirti Shivpuri et al.

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Latest spotLight

spotLights is an interview series dedicated to highlighting exciting new preprints in the biological sciences and the early-career researchers driving the work.

Find out more

spotLights episode 11: Rethinking peer review

In the latest episode of spotLights, preLighter Jonathan Townson speaks with Daniel Gorelick and Alejandra Clark, Editor-in-Chief and Managing Editor of Biology Open, respectively, and the main drivers behind the Fast & Fair peer review experiment — a community-led initiative aiming to make peer review faster, transparent, and equitable. They share…

Posted on

22 May 2025

spotLights hits episode 10

We’re excited to announce the release of episode 10 of spotLights, the latest in our special series recorded at the Biologists @ 100 conference in Liverpool. In this episode, we speak with Helena Crellin, a PhD student in the lab of Clare Buckley at the University of Cambridge. In her…

Posted on

14 May 2025

spotLights episode 9: Dr Jenny Richens

We’re pleased to share the latest episode of ‘spotLights’, our interview series highlighting the people behind the most exciting biological preprints. This episode is the second in a series recorded live at the Biologists @ 100 conference in Liverpool, which took place in March 2025. Our guest this time is…

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30 April 2025

Recent preLists

Keystone Symposium – Metabolic and Nutritional Control of Development and Cell Fate

This preList contains preprints discussed during the Metabolic and Nutritional Control of Development and Cell Fate Keystone Symposia. This conference was organized by Lydia Finley and Ralph J. DeBerardinis and held in the Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States from May 7th to 9th 2024. This meeting marked the first in-person gathering of leading researchers exploring how metabolism influences development, including processes like cell fate, tissue patterning, and organ function, through nutrient availability and metabolic regulation. By integrating modern metabolic tools with genetic and epidemiological insights across model organisms, this event highlighted key mechanisms and identified open questions to advance the emerging field of developmental metabolism.

Virginia Savy, Martin Estermann

April in preprints – the CellBio edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell cycle and division 3) cell organelles and organisation 3) cell signalling and mechanosensing 4) (epi)genetics

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March in preprints – the CellBio edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) cancer biology 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics and genomics 6) other

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Biologists @ 100 conference preList

This preList aims to capture all preprints being discussed at the Biologists @100 conference in Liverpool, UK, either as part of the poster sessions or the (flash/short/full-length) talks.