Preprint Peer Review – Biochemistry Course at UFRJ, Brazil

Communication of scientific knowledge has changed dramatically in recent decades and the public perception of scientific discoveries depends on the peer review process of articles published in scientific journals. Preprints are key vehicles for the dissemination of scientific discoveries, but they are still not properly recognized by the scientific community since peer review is very limited. On the other hand, peer review is very heterogeneous and a fundamental aspect to improve it is to train young scientists on how to think critically and how to evaluate scientific knowledge in a professional way. Thus, this course aims to: i) train students on how to perform peer review of scientific manuscripts in a professional manner; ii) develop students' critical thinking; iii) contribute to the appreciation of preprints as important vehicles for the dissemination of scientific knowledge without restrictions; iv) contribute to the development of students' curricula, as their opinions will be published and indexed on the preLights platform. The evaluations will be based on qualitative analyses of the oral presentations of preprints in the field of biochemistry deposited in the bioRxiv server, of the critical reports written by the students, as well as of the participation of the students during the preprints discussions.


List by Marcus Oliveira

Nutrient-regulated dynamics of chondroprogenitors in the postnatal murine growth plate

Takeshi Oichi, Joe Kodama, Kimberly Wilson, et al.

Selected by Alberto Rosello-Diez et al.

Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.

Selected by Laura Celotto


Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

Laura F. Mattner, Zhen Zeng, Christoph H. Mayr, et al.

Selected by Rob Hynds


The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

Claudia Carlantoni, Leon Liekfeld, Sandra A. Hemkemeyer, et al.

Selected by Andreas van Impel, Sanjay Sunil Kumar

Alumni picks – preLights 5th Birthday

This preList contains preprints that were picked and highlighted by preLights Alumni - an initiative that was set up to mark preLights 5th birthday. More entries will follow throughout February and March 2023.


List by Sergio Menchero et al.

A transcriptional and regulatory map of mouse somitogenesis

Ximena Ibarra-Soria, Elodie Thierion, Gi Fay Mok, et al.

Selected by Sergio Menchero

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by Diego Martínez

Bovine blastocyst like structures derived from stem cell cultures

Carlos A. Pinzón-Arteaga, Yinjuan Wang, Yulei Wei, et al.

Selected by Carly Guiltinan

Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

Clémentine Villeneuve, Ali Hashmi, Irene Ylivinkka, et al.

Selected by Sudeepa Nandi

Functional synapses between small cell lung cancer and glutamatergic neurons

Anna Schmitt, Vignesh Sakthivelu, Kristiano Ndoci, et al.

Selected by Jade Chan

A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.

Selected by Silvia Becca