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Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Marinelle Rodrigues, Parastoo Sabaeifard, Muhammed Sadik Yildiz, et al.

A Single Laccase Acts as a Key Component of Environmental Sensing in a Broad Host Range Fungal Pathogen

Nathaniel M. Westrick, Eddie G. Dominguez, Christina M. Hull, et al.

daf-42 is an evolutionarily young gene essential for dauer development in Caenorhabditis elegans

Daisy S. Lim, Jun Kim, Wonjoo Kim, et al.

cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane

Takeshi Nishimura, Shogo Mori, Hiromasa Shikata, et al.

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Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

Jiayue Chen, Renbo Yu, Na Li, et al.

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Flat clathrin lattices are linked to metastatic potential in colorectal cancer

Charlotte Cresens, Guillermo Solis-Fernandez, Astha Tiwari, et al.

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.