Search results

Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Selected by 19 May 2026

María Mariner-Faulí

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

Madalena Vaz Santos, Bauke V. Schomakers, Llobet Ayala Marta, et al.

Selected by 19 May 2026

Alan Leung

Human Assembloid Model of Emergent Neurotropic Enteroviruses

Christine E. Peters, Jimena Andersen, Min-Yin Li, et al.

Selected by 01 April 2026

Mitchell Sarmie

Discussion

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Selected by 11 February 2026

Isabel Paine

Discussion

Human pluripotent stem cell-derived macrophages modify development of human kidney organoids

Filipa M. Lopes, Ioannis Bantounas, Alexandra Sarov, et al.

Selected by 16 January 2026

Theodora Stougiannou

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Discussion

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, et al.

Selected by 27 October 2025

Theodora Stougiannou

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Selected by 05 August 2025

Justin Gutkowski

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Discussion

Heart Scar-In-A-Dish: Tissue Culture Platform to Study Myocardial Infarct Healing In Vitro

MJ Potter, JD Heywood, SJ Coeyman, et al.

Selected by 28 April 2025

Theodora Stougiannou

Discussion