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PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Discussion

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation

Rudolf Pisa, Tom A. Rapoport

Discussion

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Discussion

Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia

David E. Frankhouser, Dandan Zhao, Yu-Hsuan Fu, et al.

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, et al.

Environmental and Maternal Imprints on Infant Gut Metabolic Programming

Kine Eide Kvitne, Celeste Allaband, Jennifer C. Onuora, et al.

Discussion

Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle

Yangyi E. Luo, Zoe Abe-Teh, Tarek Y. Alsaghir, et al.

Discussion

Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration

Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J.Li, et al.

In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

Filip Mundt Madsen, Annelaura Bach Nielsen, Juanjuan Wang, et al.

Single-Cell Network Analysis Identifies CLEC4E as a Key Mediator of Proinflammatory mDC Responses in Influenza Infection

Subin Cho, Gabriel Laghlali, Arturo Marin, et al.