Megane Rayer

I am a postdoc in Dr. Gregg Gundersen’s lab (Columbia University). I am working on mammary gland in 3D culture. I study the mechanical role of the nucleus via the LINC complex in epithelia architecture. Before that, I did my PhD in Magali Suzanne’s lab in Toulouse (France). I found for the first time that the nucleus is relocated in basal side in apoptotic cells to serve of anchor point to a myosin cable generating an apico-basal forces, important for the drosophila leg morphogenesis. I am very interesting and very curious to understand how the nucleus can play other role than genome protector, especially through its mechanical properties. I am also interested to understand how the nuclear physical features can influence cell behaviors and morphogenesis.


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