Preprint highlights, selected by the biological community
Mitchell Sarmie
First-generation graduate from Liberia with a BSc in Biomedical Science from the University of Liberia (2022). Currently pursuing an MSc in Infectious Diseases and One Health (IDOH) under the Erasmus Mundus program. Interested in host–pathogen interactions of viruses and how these mechanisms drive disease emergence and transmission. Dedicated to advancing infectious disease research and improving public health in Liberia.
Gut microbial composition modulates food-specific CD4+ T cells in food allergy
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28 November 2025
Mitchell Sarmie, Serena Restori
A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells
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05 November 2025
Mitchell Sarmie
The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment
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20 August 2024
Mitchell Sarmie, Mohammed A. Jalloh
4 weeks
Mitchell Sarmie
The study focused on the novel finding of an MHC class II molecule (BL2*021:01) in chickens that can bind the same viral peptide in two different core conformations. This plasticity is proposed as a key determinant of resistance to MDV seen in chickens with the B21 haplotype, common in commercial breeds. However, it does not provide experimental specifics about breed, housing, prior exposure, vaccination, or medication. The primary experimental system relies on cell lines, recombinant protein expression, and birds with the B21 haplotype. If you need more methodological or experimental details, please contact the authors. You can find their emails in the preprint.