I am a cell biologist currently working as a postdoctoral researcher at Institut curie, Paris with Dr. Christophe Lamaze. My research interest lies in understanding how migrating cells read and interpret mechano-chemical stimuli.
In my Ph.D. work with Dr. Nagaraj Balasubramanian (IISER Pune, India), I discovered a novel regulation by cell-matrix adhesion on Golgi organization and function in anchorage-dependent mammalian cells (Singh et al., JCS, 2018). Findings from my thesis work could have implications in cell-matrix biology research in disease conditions and also a role in established mitotic-Golgi fragmentation pathway.
Mechanical stresses govern myoblast fusion and myotube growth
Vibha SINGH, Prasanna Padmanaban

Long range mutual activation establishes Rho and Rac polarity during cell migration
Vibha SINGH

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration
Vibha SINGH

Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly
Vibha SINGH

The actin cortex acts as a mechanical memory of morphology in confined migrating cells
Prasanna Padmanaban, Vibha SINGH

Actin dynamics sustains spatial gradients of membrane tension in adherent cells
Vibha SINGH

Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity
Vibha SINGH

Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility
Vibha SINGH

Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
Vibha SINGH

GIV•Kindlin interaction is required for Kindlin-Mediated Integrin Recognition and Activation
Vibha SINGH

WASP restricts active Rac to maintain cells’ front-rear polarisation
Vibha SINGH

Mechanical Stretch Kills Transformed Cancer Cells
Vibha SINGH

January in preprints – the CellBio edition
A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. This month, categories include: 1) biochemistry/metabolism 2) cell migration 3) cell organelles and organisation 4) cell signalling and mechanosensing 5) genetics/gene expression
List by | Barbora Knotkova et al. |
November in preprints – the CellBio edition
This is the first community-driven preList! A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading lists for researchers with an interest in cell biology. Categories include: 1) cancer cell biology 2) cell cycle and division 3) cell migration and cytoskeleton 4) cell organelles and organisation 5) cell signalling and mechanosensing 6) genetics/gene expression
List by | Felipe Del Valle Batalla et al. |