I am a cell biologist currently working as a postdoctoral researcher at Institut curie, Paris with Dr. Christophe Lamaze. My research interest lies in understanding how migrating cells read and interpret mechano-chemical stimuli.
In my Ph.D. work with Dr. Nagaraj Balasubramanian (IISER Pune, India), I discovered a novel regulation by cell-matrix adhesion on Golgi organization and function in anchorage-dependent mammalian cells (Singh et al., JCS, 2018). Findings from my thesis work could have implications in cell-matrix biology research in disease conditions and also a role in established mitotic-Golgi fragmentation pathway.
Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility
Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition