I am a cell biologist currently working as a postdoctoral researcher at Institut curie, Paris with Dr. Christophe Lamaze. My research interest lies in understanding how migrating cells read and interpret mechano-chemical stimuli.
In my Ph.D. work with Dr. Nagaraj Balasubramanian (IISER Pune, India), I discovered a novel regulation by cell-matrix adhesion on Golgi organization and function in anchorage-dependent mammalian cells (Singh et al., JCS, 2018). Findings from my thesis work could have implications in cell-matrix biology research in disease conditions and also a role in established mitotic-Golgi fragmentation pathway.
Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
GIV•Kindlin interaction is required for Kindlin-Mediated Integrin Recognition and Activation
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
WASP restricts active Rac to maintain cells’ front-rear polarisation
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Mechanical Stretch Kills Transformed Cancer Cells
Vibha SINGH
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)