I am a Postdoctoral Researcher under the supervision of Dr del Monte-Nieto Gonzalo at Australian Regenerative Medicine Institute, Monash Univerisity, Australia. I am enthusiastic about discovering new knowledge in cardiac developmental biology, which could be translated into clinical application to help people.
I obtained Ph.D. degree in molecular cell biology at the Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), South Korea, in 2019. My studies focused on characterizing the interactome of the Hippo pathway and its function during organogenesis. When joining the cardiac research field, I found a burst of excitement and inspiration. My passion is always driven by how the first heartbeat is generated and what factors control its morphogenesis from a cardiac crescent to a four-chamber heart. We attempt to classify cellular heterogeneity and the molecular network involved in cardiogenesis at an early embryonic stage using single-cell/nuclei RNA analysis. I believe if we understand the underlying mechanisms of heart development profoundly, we will find a better treatment for congenital heart disease.
Pseudo-dynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry
Yen Tran
Semaphorin3f as an intrinsic regulator of chamber-specific heart development
Yen Tran
Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
Yen Tran, Osvaldo Contreras