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Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation

Rudolf Pisa, Tom A. Rapoport

Selected by 21 November 2025

Ana Sanchez-Molina

Molecular Biology

Maturation of the glymphatic system confers innate resistance of the brain to Zika virus infection

Jhulimar Guilherme Doerl, Emanuelly Karine Campos Chaves, Vivian Antonielly Becker dos Santos, et al.

Selected by 20 November 2025

Jimeng Li

Neuroscience

VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity

Paul Palmquist-Gomes, Gaëlle Letort, Ayushi U. Hegde, et al.

Selected by 19 November 2025

Anubhav Prakash

Developmental Biology

HAK-actin, U-ExM-compatible probe to image the actin cytoskeleton

Olivier Mercey, Luc Reymond, Florent Lemaître, et al.

Selected by 17 November 2025

Kanishka Parashar

Cell Biology

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

Neuroscience

October in preprints – DevBio & Stem cell biology

Each month, preLighters with expertise across developmental and stem cell biology nominate a few recent developmental and stem cell biology (and related) preprints they’re excited about and explain in a single paragraph why. Short, snappy picks from working scientists — a quick way to spot fresh ideas, bold methods and papers worth reading in full. These preprints can all be found in the October preprint list published on the Node.

 



List by Deevitha Balasubramanian et al.

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Evolutionary Biology

Getting a head start: Craniofacial heterochrony in marsupials involves dynamic changes to molecular and cellular mechanisms underlying neural crest development

Axel H Newton, Ella R Farley, Andrew T Major, et al.

Selected by 12 November 2025

Heather Pollington

Developmental Biology

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Selected by 11 November 2025

Charis Qi

Bioinformatics

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry

Identifiability-Guided Assessment of Digital Twins in Alzheimer’s Disease Clinical Research and Care

Juliet Jiang, Jeffrey R. Petrella, Wenrui Hao, et al.

Selected by 08 November 2025

My Nguyen

Neuroscience

A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells

Anastasia Goryanin, Atlanta G. Cook, Shahriar Behboudi, et al.

Selected by 05 November 2025

Mitchell Sarmie

Immunology