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A potential anti-amyloidogenic therapy for type 2 diabetes based on the QBP1 peptide

María M. Tejero-Ojeda, Ada Bernaus Vives, Michal Wojciechowski, et al.

Discussion

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

Quentin A. Thomas, Liyang Wu, Emma Lesage, et al.

Discussion

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Discussion

A thirty-year trend of increasing clinical orientation at the National Institutes of Health

Brad L. Busse, James M. Tucker, Summer E. Allen, et al.

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Prediction of transformative breakthroughs in biomedical research

Matthew T. Davis, Brad L. Busse, Salsabil Arabi, et al.

Discussion

Cell-intrinsic compliance mechanism enables release of tensile stress to prevent tissue rupture

Chun Wai Kwan, Shunta Sakaguchi, Michiko Takeda, et al.

A drought stress-induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula)

Sijia Liu, Siamsa M. Doyle, Kathryn M. Robinson, et al.

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Discussion

Cannibalism as a mechanism to offset reproductive costs in three-spined sticklebacks

V.I. Abuwa, A. de Flamingh, E. Arredondo, et al.

Discussion

The lipidomic architecture of the mouse brain

Luca Fusar Bassini, Halima Hannah Schede, Laura Capolupo, et al.

Discussion

Self-renewal of neuronal mitochondria through asymmetric division

Tejashree Pradip Waingankar, Camryn Zurita, Angelica E. Lang, et al.

Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation

Floris Bosveld, Baptiste Tesson, Eric van Leen, et al.

Discussion