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High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Neuroscience

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, et al.

Selected by 27 October 2025

Theodora Stougiannou

Bioengineering

Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle

Yangyi E. Luo, Zoe Abe-Teh, Tarek Y. Alsaghir, et al.

Selected by 24 October 2025

Hafsa Zahid

Immunology

Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration

Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J.Li, et al.

Selected by 19 October 2025

Hafsa Zahid

Immunology

Epicardial Tcf21 facilitates cardiomyocyte dedifferentiation and heart regeneration in zebrafish

Miglė Kalvaitytė-Repečkė, Sofija Gabrilavičiūtė, Kotryna Kvederavičiūtė, et al.

Selected by 13 September 2025

Theodora Stougiannou

Cell Biology

Tumor-infiltrating CD27-IgD- regulatory B cells suppress cytotoxic CD8+T cell responses in renal cell carcinoma

Zara Baig, Isabella Withnell, Joseph C.F. Ng, et al.

Selected by 12 August 2025

Charis Qi

Immunology

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Selected by 05 August 2025

Justin Gutkowski

Developmental Biology

The essential role of connective-tissue cells during axolotl limb regeneration

Damián García-García, Dunja Knapp, Minjoo Kim, et al.

Selected by 26 June 2025

Dhanuush Balakannan

Developmental Biology

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation

Marika Oksanen, Francesca Mastropasqua, Krystyna Mazan-Mamczarz, et al.

Selected by 24 June 2025

Candy Rutihinda et al.

Molecular Biology

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Neuroscience

An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer

Wenyan Xie, Xin Yu, Qingxin Yang, et al.

Selected by 20 May 2025

Roberto Amadio

Cancer Biology

A conserved differentiation program facilitates inhibitory neuron production in the developing mouse and human cerebellum

Jens Bager Christensen, Alex P.A. Donovan, Marzieh Moradi, et al.

Selected by 15 May 2025

Jethro Lundie-Brown

Developmental Biology