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A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells

Rita Berkachy, Vishwas Mishra, Priyanka Biswas, et al.

Gut microbial composition modulates food-specific CD4⁺ T cells in food allergy

Alexa R Weingarden, Flannery S Dahlberg, Caroline N Broude, et al.

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, et al.

Actin Counters Geometry to Guide Plant Cell Division

Camila Goldy, Samantha Moulin, Yutaro Shimizu, et al.

Discussion

Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation

Rudolf Pisa, Tom A. Rapoport

Discussion

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Discussion

A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells

Anastasia Goryanin, Atlanta G. Cook, Shahriar Behboudi, et al.

Computational design of pH-sensitive binders

Green Ahn, Brian Coventry, Ella Haefner, et al.

Matrix viscoelasticity regulates dendritic cell migration and immune priming

Wei-Hung Jung, Emie Humann, Joshua M Price, et al.

Discussion

Longitudinal single cell RNA-sequencing reveals evolution of micro- and macro-states in chronic myeloid leukemia

David E. Frankhouser, Dandan Zhao, Yu-Hsuan Fu, et al.

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Discussion