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Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.



Selected by Preethi Krishnaraj

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.



Selected by Louise Moyle et al.

TEMPO: A system to sequentially label and genetically manipulate vertebrate cell lineages

Isabel Espinosa-Medina, Daniel Feliciano, Carla Belmonte-Mateos, et al.



Selected by Julia Grzymkowski

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, et al.



Selected by Jeffrey Calhoun

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.



Selected by Lorenzo Lafranchi

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.



Selected by Fabio Liberante

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