Filtered by crispr category

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by Louise Moyle et al.

TEMPO: A system to sequentially label and genetically manipulate vertebrate cell lineages

Isabel Espinosa-Medina, Daniel Feliciano, Carla Belmonte-Mateos, et al.

Selected by Julia Grzymkowski

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, et al.

Selected by Jeffrey Calhoun

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.

Selected by Lorenzo Lafranchi

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.

Selected by Fabio Liberante

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Selected by Jesus Victorino

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Özgen Deniz, Mamataz Ahmed, Christopher D. Todd, et al.

Selected by Jesus Victorino

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Selected by Sergio Menchero