Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases
Selected by
Louise Moyle et al.
TEMPO: A system to sequentially label and genetically manipulate vertebrate cell lineages
Selected by
Julia Grzymkowski
Saturation variant interpretation using CRISPR prime editing
Selected by
Jeffrey Calhoun
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens
Selected by
Lorenzo Lafranchi
Precise genomic deletions using paired prime editing
Selected by
Fabio Liberante
Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes
Selected by
Jesus Victorino
Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia
Selected by
Jesus Victorino
A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation
Selected by
Sergio Menchero