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PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Selected by 11 February 2026

Isabel Paine

Neuroscience

The lipidomic architecture of the mouse brain

Luca Fusar Bassini, Halima Hannah Schede, Laura Capolupo, et al.

Selected by 09 February 2026

CRM UoE Journal Club et al.

Neuroscience

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFRVIII-Mutated Glioblastoma Cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, et al.

Selected by 21 January 2026

Dina Kabbara

Cancer Biology

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Selected by 02 December 2025

Siddharth Singh

Evolutionary Biology

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Selected by 01 December 2025

Jawdat Sandakly

Developmental Biology

Gut microbial composition modulates food-specific CD4+ T cells in food allergy

Alexa R Weingarden, Flannery S Dahlberg, Caroline N Broude, et al.

Selected by 28 November 2025

Mitchell Sarmie, Serena Restori

Immunology

ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion

Daniel A. Reed, Anna E. Howell, Nadia Kuepper, et al.

Selected by 27 November 2025

Sharvari Pitke

Cancer Biology

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

Neuroscience

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Selected by 11 November 2025

Charis Qi

Bioinformatics

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry

A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells

Anastasia Goryanin, Atlanta G. Cook, Shahriar Behboudi, et al.

Selected by 05 November 2025

Mitchell Sarmie

Immunology