19th International Congress of Developmental Biology

From Gastruloids to Organoids

A combined transcriptional and dynamic roadmap of single human pancreatic endocrine progenitors reveals proliferative capacity and differentiation continuum

Belin Selcen Beydag-Tasöz, Joyson Verner D’Costa, Lena Hersemann, Federica Luppino, Yung Hae Kim, Christoph Zechner, Anne Grapin-Botton

https://www.biorxiv.org/content/10.1101/2021.12.15.472220v1

Reconstituting human somitogenesis in vitro

Yoshihiro Yamanaka, Kumiko Yoshioka-Kobayashi, Sofiane Hamidi, Sirajam Munira, Kazunori Sunadome, Yi Zhang, Yuzuru Kurokawa, Ai Mieda, Jamie L. Thompson, Janet Kerwin, Steven Lisgo, Takuya Yamamoto, Naomi Moris, Alfonso Martinez-Arias, Taro Tsujimura, Cantas Alev

https://www.biorxiv.org/content/10.1101/2022.06.03.494621v1

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals

Jorge Lázaro, Maria Costanzo, Marina Sanaki-Matsumiya, Charles Girardot, Masafumi Hayashi, Katsuhiko Hayashi, Sebastian Diecke, Thomas B. Hildebrandt, Giovanna Lazzari, Jun Wu, Stoyan Petkov, Rüdiger Behr, Vikas Trivedi, Mitsuhiro Matsuda, Miki Ebisuya

https://www.biorxiv.org/content/10.1101/2022.10.13.512072v1

Morphogenesis

Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven (un)jamming

Diana Pinheiro, Roland Kardos, Édouard Hannezo, Carl-Philipp Heisenberg

https://www.biorxiv.org/content/10.1101/2022.05.16.492018v1

Evo-Devo

Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration

Miguel Salinas-Saavedra, Febrimarsa, Gabriel Krasovec, Helen R Horkan, Andreas D Baxevanis, Uri Frank

https://www.biorxiv.org/content/10.1101/2022.09.02.506310v1

Cell and Tissue Mechanics

STRESS, an automated geometrical characterization of deformable particles for in vivo measurements of cell and tissue mechanical stresses

Ben Gross, Elijah Shelton, Carlos Gomez, Otger Campàs

https://www.biorxiv.org/content/10.1101/2021.03.26.437148v1

A nuclear jamming transition in vertebrate organogenesis

Sangwoo Kim, Rana Amini, Otger Campàs

https://www.biorxiv.org/content/10.1101/2022.07.31.502244v1

Development, Nutrition, and Metabolism

DHFR metabolic activity controls neurogenic transitions in the developing Human and mouse neocortex

Sulov Saha, Thomas Jungas, David Ohayon, Christophe Audouard, Tao Ye, Mohamad-Ali Fawal, Alice Davy

https://www.biorxiv.org/content/10.1101/2022.06.22.497156v1

Neural Development

TEMPO: A system to sequentially label and genetically manipulate vertebrate cell lineages

Isabel Espinosa-Medina, Daniel Feliciano, Carla Belmonte-Mateos, Jorge Garcia-Marques, Benjamin Foster, Rosa Linda Miyares, Cristina Pujades, Minoru Koyama, Tzumin Lee

https://www.biorxiv.org/content/10.1101/2021.10.27.466134v1

Species-specific mitochondria dynamics and metabolism regulate the timing of neuronal development

Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Martyna Ditkowska, Katlijn Vints, Suresh Poovathingal, Vaiva Gaspariunaite, Matthew Bird, Nikky Corthout, Pieter Vermeersch, Kristofer Davie, Natalia V. Gounko, Stein Aerts, Bart Ghesquière, Sarah-Maria Fendt, Pierre Vanderhaeghen

https://www.biorxiv.org/content/10.1101/2021.12.27.474246v1

Robustness and Plasticity

Proteostasis governs differential temperature sensitivity across embryonic cell types

Michael W. Dorrity, Lauren M. Saunders, Madeleine Duran, Sanjay R. Srivatsan, Brent Ewing, Christine Queitsch, Jay Shendure, David W. Raible, David Kimelman, Cole Trapnell

https://www.biorxiv.org/content/10.1101/2022.08.04.502669v1

Signalling in Development

OptIC Notch reveals mechanism that regulates receptor interactions with CSL.

Jonathan Marcus Townson, Maria J Gomez-Lamarca, Sarah J Bray

https://www.biorxiv.org/content/10.1101/2023.02.20.528063v1

Keynotes

Sequential And Directional Insulation By Conserved CTCF Sites Underlies The Hox Timer In Pseudo-Embryos

Hocine Rekaik, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Célia Bochaton, Denis Duboule

https://www.biorxiv.org/content/10.1101/2022.08.29.505673v1.full

The evolution of ovary-biased gene expression in Hawaiian Drosophila

Samuel H. Church, Catriona Munro, Casey W. Dunn, Cassandra G. Extavour

https://www.biorxiv.org/content/10.1101/2021.11.30.470652v3

Reconstruction and deconstruction of human somitogenesis in vitro

Yuchuan Miao, Yannis Djeffal, Alessandro De Simone, Kongju Zhu, Andrew Silberfeld, Jong Gwan Lee, Jyoti Rao, Oscar A. Tarazona, Alessandro Mongera, Pietro Rigoni, Margarete Diaz-Cuadros, Laura Min Sook Song, Stefano Di Talia, Olivier Pourquié

https://www.biorxiv.org/content/10.1101/2022.05.11.491561v1