From stem cells to human development 2022

Reconstituting human somitogenesis in vitro

Yoshihiro Yamanaka, Kumiko Yoshioka-Kobayashi, Sofiane Hamidi, Sirajam Munira, Kazunori Sunadome, Yi Zhang, Yuzuru Kurokawa, Ai Mieda, Jamie L. Thompson, Janet Kerwin, Steven Lisgo, Takuya Yamamoto, Naomi Moris, Alfonso Martinez-Arias, Taro Tsujimura, Cantas Alev

https://www.biorxiv.org/content/10.1101/2022.06.03.494621v1

Mechanics of human embryo compaction

Julie Firmin, Nicolas Ecker, Diane Rivet Danon, Virginie Barraud Lange, Hervé Turlier, Catherine Patrat, Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2022.01.09.475429v1

NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naïve pluripotent stem cells

Katsiaryna Maskalenka, Gökberk Alagöz, Felix Krueger, Joshua Wright, Maria Rostovskaya, Asif Nakhuda, Adam Bendall, Christel Krueger, Simon Walker, Aylwyn Scally, Peter J. Rugg-Gunn

https://www.biorxiv.org/content/10.1101/2022.08.18.504441v1

Maturation of human intestinal epithelium from pluripotency in vitro

Umut Kilik, Qianhui Yu, Rene Holtackers, Makiko Seimiya, Aline Xavier da Silveira dos Santos, Barbara Treutlein, Jason R. Spence, J. Gray Camp

https://www.biorxiv.org/content/10.1101/2021.09.24.460132v1

Multimodal spatiotemporal phenotyping of human organoid development

Philipp Wahle, Giovanna Brancati, Christoph Harmel, Zhisong He, Gabriele Gut, Aline Santos, Qianhui Yu, Pascal Noser, Jonas Simon Fleck, Bruno Gjeta, Dinko Pavlinić, Simone Picelli, Maximilian Hess, Gregor Schmidt, Tom Lummen, Yanyan Hou, Patricia Galliker, Magdalena Renner, Lucas Pelkmans, Barbara Treutlein, J. Gray Camp

https://www.biorxiv.org/content/10.1101/2022.03.16.484396v1

A human embryonic limb cell atlas resolved in space and time

Bao Zhang, Peng He, John E Lawrence, Shuaiyu Wang, Elizabeth Tuck, Brian Williams, Kenny Roberts, Vitalii Kleshchevnikov, Lira Mamanova, Liam Bolt, Krzysztof Polanski, Rasa Elmentaite, Eirini S Fasouli, Martin Prete, Xiaoling He, Nadav Yayon, Yixi Fu, Hao Yang, Chen Liang, Hui Zhang, David R. FitzPatrick, Helen Firth, Andrew Dean, Roger A Barker, Mekayla A Storer, Barbara J Wold, Hongbo Zhang, Sarah A Teichmann

https://www.biorxiv.org/content/10.1101/2022.04.27.489800v1

CellOracle: Dissecting cell identity via network inference and in silico gene perturbation

Kenji Kamimoto, Christy M. Hoffmann, Samantha A. Morris

https://www.biorxiv.org/content/10.1101/2020.02.17.947416v3

From Gradient to Sectioning in CUBE: Workflow for Generating and Imaging Organoid with Localized Differentiation

Isabel Koh, Masaya Hagiwara

https://www.biorxiv.org/content/10.1101/2022.09.06.506732v1

Localization of multiple hydrogels with MultiCUBE platform spatially guides 3D tissue morphogenesis in vitro

Kasinan Suthiwanich, Masaya Hagiwara

https://www.biorxiv.org/content/10.1101/2022.09.08.507064v1

A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

Peng He, Kyungtae Lim, Dawei Sun, Jan Patrick Pett, Quitz Jeng, Krzysztof Polanski, Ziqi Dong, Liam Bolt, Laura Richardson, Lira Mamanova, Monika Dabrowska, Anna Wilbrey-Clark, Elo Madissoon, Zewen Kelvin Tuong, Emma Dann, Chenqu Suo, Isaac Goh Kai’En, Xiaoling He, Roger Barker, Sarah A Teichmann, John C. Marioni, Kerstin B Meyer, Emma L Rawlins

https://www.biorxiv.org/content/10.1101/2022.01.11.474933v1

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

Kyungtae Lim, Walfred Tang, Dawei Sun, Peng He, Sarah A. Teichmann, John C. Marioni, Kerstin B. Meyer, Emma L. Rawlins

https://www.biorxiv.org/content/10.1101/2021.06.30.450501v1

Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

Renee F.C. Hein, Ansley S. Conchola, Alexis Fine, Zhiwei Xiao, Tristan Frum, Charlie J. Childs, Yu-Hwai Tsai, Emily M. Holloway, Sha Huang, John Mahoney, Jason R. Spence

https://www.biorxiv.org/content/10.1101/2022.02.25.481981v1

This paper has just been published in Development.