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High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Neuroscience

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, et al.

Selected by 27 October 2025

Theodora Stougiannou

Bioengineering

Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle

Yangyi E. Luo, Zoe Abe-Teh, Tarek Y. Alsaghir, et al.

Selected by 24 October 2025

Hafsa Zahid

Immunology

Normal aging increases white matter microglial reaction and perivascular macrophages in the microcebe primate

Léo Dupuis, Lolie Garcia, Fanny Petit, et al.

Selected by 22 October 2025

Isabel Paine

Neuroscience

Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration

Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J.Li, et al.

Selected by 19 October 2025

Hafsa Zahid

Immunology

TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling

Janik Engelmann, Jennifer Zarrer, Max Schmerder, et al.

Selected by 14 October 2025

André Luiz Amorim Costa, Marcus Oliveira

Immunology

Tandem duplication of serpin genes yields functional variation and snake venom inhibitors

Meilyn S. Ward, Matthew L. Holding, Laura M. Haynes, et al.

Selected by 09 October 2025

Daniel Osorno Valencia, Marcus Oliveira

Evolutionary Biology

In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

Filip Mundt Madsen, Annelaura Bach Nielsen, Juanjuan Wang, et al.

Selected by 07 October 2025

TheLangeLab et al.

Cancer Biology

Polyamine depletion inhibits norovirus infection by blocking virus-induced apoptosis

Maryna Chaika, Heike Laschin, Marina Pekelis, et al.

Selected by 02 October 2025

Leonie Brüne

Immunology

Single-Cell Network Analysis Identifies CLEC4E as a Key Mediator of Proinflammatory mDC Responses in Influenza Infection

Subin Cho, Gabriel Laghlali, Arturo Marin, et al.

Selected by 29 September 2025

Charis Qi

Systems Biology

Targeting RhoA activity rejuvenates aged hematopoietic stem cells

Eva Mejía-Ramírez, Pablo Iañez Picazo, Barbara Walter, et al.

Selected by 24 September 2025

Vibha SINGH

Cell Biology

Epicardial Tcf21 facilitates cardiomyocyte dedifferentiation and heart regeneration in zebrafish

Miglė Kalvaitytė-Repečkė, Sofija Gabrilavičiūtė, Kotryna Kvederavičiūtė, et al.

Selected by 13 September 2025

Theodora Stougiannou

Cell Biology