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Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

Neuroscience

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Evolutionary Biology

Getting a head start: Craniofacial heterochrony in marsupials involves dynamic changes to molecular and cellular mechanisms underlying neural crest development

Axel H Newton, Ella R Farley, Andrew T Major, et al.

Selected by 12 November 2025

Heather Pollington

Developmental Biology

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Selected by 11 November 2025

Charis Qi

Bioinformatics

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry

Identifiability-Guided Assessment of Digital Twins in Alzheimer’s Disease Clinical Research and Care

Juliet Jiang, Jeffrey R. Petrella, Wenrui Hao, et al.

Selected by 08 November 2025

My Nguyen

Neuroscience
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spotLights is an interview series dedicated to highlighting exciting new preprints in the biological sciences and the early-career researchers driving the work.

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- How do membrane actin protrusions initiate T-cells signalling? - What does RhoA have to do with nuclear envelope tensions in stem cells? - Does advanced microscopy help study mechano-signalling - and how? - Why did the authors decide to preprint their research?   Welcome to our September mix of…

Posted on 1 September 2025

Join the preLights community: Call for applications

Are you an early-career researcher passionate about science communication, preprints and open science? preLights, The Company of Biologists’ preprint highlighting service, is growing, and we want you to be part of our community! Since 2018, we’ve published over 1,600 preLight posts, sparking conversations between preprint authors and researchers worldwide. Now,…

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preLights meets FocalPlane features… – On 4 September

preLights have teamed up with FocalPlane, our sister community site, to hold a collaborative FocalPlane features... This webinar will be hosted by Felipe Del Valle Batalla (University of Edinburgh, UK) and Vibha Singh (Princess Margaret Cancer Research Tower (UHN), Canada), two members of the preLights community (known as preLighters), who…

Posted on 28 August 2025

Recent preLists

October in preprints – DevBio & Stem cell biology

Each month, preLighters with expertise across developmental and stem cell biology nominate a few recent developmental and stem cell biology (and related) preprints they’re excited about and explain in a single paragraph why. Short, snappy picks from working scientists — a quick way to spot fresh ideas, bold methods and papers worth reading in full. These preprints can all be found in the October preprint list published on the Node.

 



List by Deevitha Balasubramanian et al.

October in preprints – Cell biology edition

Different preLighters, with expertise across cell biology, have worked together to create this preprint reading list for researchers with an interest in cell biology. This month, most picks fall under (1) Cell organelles and organisation, followed by (2) Mechanosignaling and mechanotransduction, (3) Cell cycle and division and (4) Cell migration

 



List by Matthew Davies et al.

September in preprints – Cell biology edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading list. This month, categories include: (1) Cell organelles and organisation, (2) Cell signalling and mechanosensing, (3) Cell metabolism, (4) Cell cycle and division, (5) Cell migration

 



List by Sristilekha Nath et al.

August in preprints – Cell biology edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading list for researchers with an interest in cell biology. This month, categories include: (1) Cancer biology (2) Mechanosignaling and mechanotransduction (3) Cell organelles and organisation

 



List by Vibha SINGH, Matthew Davies
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