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2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Discussion

Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Discussion

cgas recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Discussion

Nuclear soluble cgas senses DNA virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, et al.

STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

AND

The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.

Discussion

ROS production by localized SCHENGEN receptor module drives lignification at subcellular precision

Satoshi Fujita, Damien De Bellis, Kai H. Edel, et al.

Discussion

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, et al.

Discussion

Human DNA-PK activates a STING-independent DNA sensing pathway

Katelyn Burleigh, Joanna H. Maltbaek, Stephanie Cambier, et al.

Discussion

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Discussion

A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spider Parasteatoda tepidariorum

Christian L. B. Paese, Anna Schoenauer, Daniel J. Leite, et al.