Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP
Selected by
Roberto Amadio
cgas recruitment to micronuclei is dictated by pre-existing nuclear chromatin status
Selected by
Roberto Amadio
Nuclear soluble cgas senses DNA virus infection
Selected by
Roberto Amadio
STING mediates immune responses in a unicellular choanoflagellate
AND
The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis
Selected by
Connor Rosen
ROS production by localized SCHENGEN receptor module drives lignification at subcellular precision
Selected by
Marc Somssich
Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling
Selected by
Yasmin Lau
Human DNA-PK activates a STING-independent DNA sensing pathway
Selected by
Connor Rosen
SLC19A1 is a cyclic dinucleotide transporter
AND
SLC19A1 is an importer of the immunotransmitter cGAMP
AND
2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1
Selected by
Connor Rosen
A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spider Parasteatoda tepidariorum
Selected by
Erik Clark