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Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Synthetic Biology

Developmental conversion of the nucleolus into an RNA Polymerase II transcriptional platform in Drosophila spermatocytes

Jaclyn M. Fingerhut, Jun I. Park, Rebecca Y. Li, et al.

Selected by 22 June 2026

Panagiotis Giannios

Developmental Biology

CENP-B binds hairpin motifs in chromosome arms influencing gene expression

Lillian Wu, Karen A Lane, Reyhan Muhammad, et al.

Selected by 04 June 2026

Pierre Caron

Cell Biology

Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of chromatin in Epithelium

Elina Mäntylä, Sanna Korpela, Anna Rekonen, et al.

Selected by 02 June 2026

Abby Hein

Cell Biology

Evolutionary landscapes of zygotic genome activation across animals

Israel Campo-Bes, Federica Mantica, Jon Permanyer, et al.

Selected by 26 May 2026

Panagiotis Giannios

Evolutionary Biology

chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

Jethro Lundie-Brown, Rosalind Drummond, John-Poul Ng-Blichfeldt, et al.

Selected by 21 May 2026

Reinier Prosee, Jethro Lundie-Brown

Developmental Biology

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Selected by 19 May 2026

María Mariner-Faulí

Developmental Biology

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

Madalena Vaz Santos, Bauke V. Schomakers, Llobet Ayala Marta, et al.

Selected by 19 May 2026

Alan Leung

Developmental Biology

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

Jeremy A. Hollis, Jason A. Stonick, Irini Topalidou, et al.

Selected by 21 April 2026

Reinier Prosee

Evolutionary Biology

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

Quentin A. Thomas, Liyang Wu, Emma Lesage, et al.

Selected by 01 April 2026

Élise Jeanne Pouponnot, Pierre Caron

Cell Biology

Classical enhancers couple cis-regulatory logic with transcriptional condensates and 3D genome architecture

Ville Tiusanen, Divyesh Patel, Jihan Xia, et al.

Selected by 22 March 2026

Siddharth Singh

Cell Biology

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Selected by 01 December 2025

Jawdat Sandakly

Developmental Biology