Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action
Selected by
13 February 2025
Roberto Amadio

Coxiella burnetii actively blocks IL-17-induced oxidative stress in macrophages
Selected by
16 May 2023
UofA IMB565

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis
Selected by
09 December 2020
Connor Rosen

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Selected by
14 July 2020
Louise Fraser

Mutual Potentiation of Plant Immunity by Cell-surface and Intracellular Receptors
AND
Pattern-recognition receptors are required for NLR-mediated plant immunity
Selected by
29 April 2020
Sruthi S Balakrishnan
