Search results

Wide-ranging behavioral dysfunction in two mouse models of pathological human variants in the GRIK2 kainate receptor gene

Brynna T. Webb, Hieu Trinh, Emily A. Breach, et al.

Selected by 18 August 2025

Pushpinder Singh

Discussion

FUS Mislocalization Rewires a Cortical Gene Network to Drive 2 Cognitive and Behavioral Impairment in ALS

Raphaelle CASSEL, Félicie LORENC, Aurélie BOMBARDIER, et al.

Selected by 14 July 2025

Taylor Stolberg

Discussion

A prophage-encoded anti-phage defense system that prevents phage DNA packaging by targeting the terminase complex

Gil Azulay, Nadejda Sigal, Keren Tzohar Rabinovich, et al.

Selected by 19 May 2025

Briana Guzman et al.

Discussion

TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stability

Charlie Moffatt, Ankita Arora, Katherine F. Vaeth, et al.

Selected by 10 April 2025

Felipe Del Valle Batalla

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

Friederike M. C. Benning, Tristan A. Bell, Tran H. Nguyen, et al.

Selected by 07 March 2025

Barbora Knotkova

Discussion

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Discussion

Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods

Constantin Ahlmann-Eltze, Wolfgang Huber, Simon Anders

Selected by 11 November 2024

Benjamin Dominik Maier

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Marco De Donatis, et al.

Selected by 07 October 2024

Simon Cleary

The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

Joelle Lo, Katherine F. Vaeth, Gurprit Bhardwaj, et al.

Selected by 24 September 2024

Felipe Del Valle Batalla

Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA

Brett T. Wisniewski, Laura L. Lackner

Selected by 30 August 2024

Leeba Ann Chacko

Discussion

Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Emily N. P. Prowse, Abdullah R. Chaudhary, David Sharon, et al.

Selected by 21 August 2024

Abhishek Poddar

Discussion

TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development

Canan Doganli, Daniel A. Baird, Yeasmeen Ali, et al.

Selected by 16 August 2024

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