EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
Jennifer Ann Black
SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species
Selected by
Zhang-He Goh
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
Selected by
Divya Pathak, Barbora Knotkova
Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane
AND
Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants
Selected by
Marc Somssich, Gwendolyn K. Kirschner
Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing
Selected by
Preethi Krishnaraj
Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease
Selected by
Fiona Macleod
Laboratory evolution of flies to morphogen dosage via rapid maternal changes reveals predictable outcomes
Selected by
Girish Kale
Actin nucleators safeguard replication forks by limiting nascent strand degradation
Selected by
Roberto Amadio
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis
Selected by
Pierre Caron
Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing
Selected by
Kerryn Elliott
Alumni
The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling
Selected by
Andreas van Impel, Sanjay Sunil Kumar
Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis
Selected by
Martin Estermann