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Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur



Selected by Matthew Davies

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.



Selected by Audrey Noireterre

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.



Selected by Pierre Caron

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley



Selected by Benjamin Dominik Maier

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

Danielle L. Porier, Awadalkareem Adam, Lin Kang, et al.



Selected by Lucy Bowden
Alumni

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.



Selected by Samantha Seah et al.

Bovine blastocyst like structures derived from stem cell cultures

Carlos A. Pinzón-Arteaga, Yinjuan Wang, Yulei Wei, et al.



Selected by Carly Guiltinan

Restructuring of an asymmetric neural circuit during associative learning

Leo T.H. Tang, Garrett A. Lee, Steven J. Cook, et al.



Selected by Chee Kiang Ewe

Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.



Selected by Nate Mullin

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellerman, et al.



Selected by Ilaria Di Meglio

Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal

Arunava Bandyopadhaya, Vijay K Singh, Arijit Chakraborty, et al.



Selected by Joao Mello-Vieira

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