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PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Selected by 29 December 2025

Vibha SINGH

Cell Biology

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Wei Zheng, Igor Siwanowicz, et al.

Selected by 12 December 2025

Muhammed Sinan Malik

Neuroscience

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors

Koji Matsuda, Chung-Han Wang, Atsushi Toyoda, et al.

Selected by 27 October 2025

Muhammed Sinan Malik

Neuroscience

Optogenetic control of mechanotransduction based on light-induced homodimerization of talin

Ryosuke Nishimura, Samuel F. H. Barnett, Kashish Jain, et al.

Selected by 21 July 2025

Barbora Knotkova, Sonhita Chakraborty

Cell Biology

Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion

Jessica Wagner, Konstantina Feller, Nicole Schrenke, et al.

Selected by 25 April 2025

Vibha SINGH

Cancer Biology

Long range mutual activation establishes Rho and Rac polarity during cell migration

Henry De Belly, Andreu Fernandez Gallen, Evelyn Strickland, et al.

Selected by 22 October 2024

Vibha SINGH

Cell Biology

Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity

Jonathan Kuhn, Parijat Banerjee, Andrew Haye, et al.

Selected by 07 March 2024

Vibha SINGH

Cell Biology

Sucrose overconsumption impairs feeding circuit dynamics and promotes palatable food intake

Carolyn M. Lorch, Nikolas W. Hayes, Jessica L. Xia, et al.

Selected by 11 July 2023

Cláudia Gil

Molecular Biology

Actin-driven protrusions generate rapid long-range membrane tension propagation in cells

Henry De Belly, Shannon Yan, Hudson Borja da Rocha, et al.

Selected by 23 November 2022

Nicolaes Hyun-Kee Min

Cell Biology

Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration

Rituraj Marwaha, Simran Rawal, Purnati Khuntia, et al.

Selected by 12 September 2022

Jade Chan

Cell Biology

Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.

Selected by 17 May 2022

Ines Jmel-Boyer

Cell Biology

A persistent behavioral state enables sustained predation of humans by mosquitoes

Trevor R. Sorrells, Anjali Pandey, Adriana Rosas-Villegas, et al.

Selected by 15 January 2022

Dinesh Natesan

Neuroscience