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Filtered by pharmacology and toxicology category

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

Pharmacology and Toxicology

Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms

Keirah E. Bartlett, Adam Westhorpe, Mark C. Wilkinson, et al.

Selected by 13 January 2026

Daniel Osorno Valencia

Pharmacology and Toxicology

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis

Diana Angelica Aguilar-Ayala, Marie Sylvianne Rabodoarivelo, Maxime R. Eveque-Mourroux, et al.

Selected by 24 November 2025

Zhang-He Goh

Pharmacology and Toxicology

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Evolutionary Biology

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry