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The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.



Selected by Zhang-He Goh

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein



Selected by Zhang-He Goh

Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model

Kristina M. Bigelow, Rokeya Tasneen, Yong S. Chang, et al.



Selected by Zhang-He Goh

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.



Selected by Zhang-He Goh

A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite

Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, et al.



Selected by Zhang-He Goh

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

Shengsheng Lu, Xiaoyan Pan, Daiwei Chen, et al.



Selected by Zhang-He Goh

The antimicrobial peptide DGL13K is active against resistant gram-negative bacteria and subinhibitory concentrations stimulate bacterial growth without causing resistance

Sven-Ulrik Gorr, Hunter V. Brigman, Jadyn C. Anderson, et al.



Selected by Zhang-He Goh
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