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Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

Elisabetta Mereu, Atefeh Lafzi, Catia Moutinho, et al.

AND

Systematic comparative analysis of single cell RNA-sequencing methods

Jiarui Ding, Xian Adiconis, Sean K. Simmons, et al.

Developmentally regulated Shh expression is robust to TAD perturbations

Iain Williamson, Lauren Kane, Paul S. Devenney, et al.

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Discussion

Specific Disruption of Established P. aeruginosa Biofilms Using Polymer-Attacking Enzymes

Kristin N. Kovach, Derek Fleming, Kendra P. Rumbaugh, et al.

Discussion

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

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Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

Mitotic exit is controlled during anaphase by an Aurora B-Cyclin B1/Cdk1 crosstalk

Olga Afonso, Liam P. Cheeseman, Luísa T. Ferreira, et al.

Human DNA-PK activates a STING-independent DNA sensing pathway

Katelyn Burleigh, Joanna H. Maltbaek, Stephanie Cambier, et al.

Discussion

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, et al.

Preformed Chromatin Topology Assists Transcriptional Robustness of Shh during Limb Development

Christina Paliou, Philine Guckelberger, Robert Schöpflin, et al.

A unicellular relative of animals generates an epithelium-like cell layer by actomyosin-dependent cellularization

Omaya Dudin, Andrej Ondracka, Xavier Grau-Bové, et al.

Over-activation of BMP signaling in neural crest cells precipitates heart outflow tract septation

Jean Francois Darrigrand, Mariana Valente, Pauline Martinez, et al.

Discussion

Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Kelsey M. Tyssowski, Jesse M. Gray

Discussion