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Molecular Parasitology Meeting 2020 Woods Hole

Parasitology @Molecular Parasitology Meeting 2020

List by Mariana De Niz, Gautam Dey

Preprints:

A modification to the life cycle of the parasite Trypanosoma brucei

Sarah Schuster, Ines Subota, Jaime Lisack, Henriette Zimmermann, Christian Reuter, Brooke Morriswood, Markus Engstler

https://www.biorxiv.org/content/10.1101/717975v1

N6-methyladenosine in poly(A) tails stabilize VSG transcripts

Idalio J. Viegas, Juan Pereira de Macedo, Mariana De Niz, João A. Rodrigues, Francisco Aresta-Branco, Samie R. Jaffrey, Luisa M. Figueiredo

https://www.biorxiv.org/content/10.1101/2020.01.30.925776v1

A novel essential RNA-binding protein complex in Trypanosoma brucei

Kathrin Bajak, Kevin Leiss, Christine Clayton, Esteban Erben

https://www.biorxiv.org/content/10.1101/2020.05.19.104984v1

Trypanosoma cruzi senses intracellular heme levels and regulates heme homeostasis by modulating TcHTE protein expression

Lucas Pagura, Evelyn Tevere, Marcelo L. Merli, Julia A. Cricco

https://www.biorxiv.org/content/10.1101/2020.01.10.901934v2

Exploring the evolution and adaptive role of mosaic aneuploidy in a clonal Leishmania donovani population using high throughput single cell genome sequencing

Gabriel H. Negreira, Pieter Monsieurs, Hideo Imamura, Ilse Maes, Nada Kuk, Akila Yagoubat, Frederik Van den Broeck, Yvon Sterkers, Jean-Claude Dujardin, Malgorzata A. Domagalska

https://www.biorxiv.org/content/10.1101/2020.03.05.976233v1

Single Cell RNA-sequencing reveals cellular heterogeneity, stage transition and antigenic variation during stress adaptation in synchronized Plasmodium falciparum

Mukul Rawat, Ashish Srivastava, Ishaan Gupta, Krishanpal Karmodiya

https://www.biorxiv.org/content/10.1101/752543v1

AMP-activated protein kinase: A key enzyme to manage nutritional stress responses in parasites with complex life cycles

Tamara Sternlieb, Alejandra C. Schoijet, Patricio D. Genta, Guillermo D. Alonso

https://www.biorxiv.org/content/10.1101/2020.04.08.032284v1

The ROP16III-dependent early immune response determines the sub-acute CNS immune response and type III Toxoplasma gondii survival

Shraddha Tuladhar, Joshua A. Kochanowsky, Apoorva Bhaskara, Yarah Ghotmi, Anita A. Koshy

https://www.biorxiv.org/content/10.1101/645390v1

Interplay of the Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection

Jyoti Pant, Marie Samanovic, Maria T Nelson, Mert K Keceli, Joseph Verdi, Stephen M. Beverley, Jayne Raper

https://www.biorxiv.org/content/10.1101/2020.07.02.184358v1

The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae

Gregory L. Sousa, Ritika Bishnoi, Richard H. G. Baxter, Michael Povelones

https://www.biorxiv.org/content/10.1101/2020.07.14.203380v1

Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum

Thomas C. A. Blake, Silvia Haase, Jake Baum

https://www.biorxiv.org/content/10.1101/2020.06.25.171900v1

Complexome profile of Toxoplasma gondii mitochondria identifies a divergent cytochrome bc1 complex

Andrew E. Maclean, Hannah R. Bridges, Mariana F. Silva, Shujing Ding, Judy Hirst, Lilach Sheiner

https://www.biorxiv.org/content/10.1101/2020.08.17.252163v2

Loss of a conserved MAPK causes catastrophic failure in assembly of a specialized cilium-like structure in Toxoplasma gondii

William J. O’Shaughnessy, Xiaoyu Hu, Tsebaot Beraki, Matthew McDougal, Michael L. Reese

https://www.biorxiv.org/content/10.1101/2020.02.02.931022v1

Gut metabolites influence susceptibility of neonatal mice to cryptosporidiosis

Kelli L. VanDussen, Lisa J. Funkhouser-Jones, Marianna E. Akey, Deborah A. Schaefer, Kevin Ackman, Michael W. Riggs, Thaddeus S. Stappenbeck, L. David Sibley

https://www.biorxiv.org/content/10.1101/2020.09.11.294462v1

A Parasite Coat Protein Binds Suramin to Confer Drug Resistance

Johan Zeelen, Monique van Straaten, Joseph Verdi, Alexander Hempelmann, Hamidreza Hashemi, Kathryn Perez, Philip D. Jeffrey, Silvan Hälg, Natalie Wiedemar, Pascal Mäser, F. Nina Papavasiliou, C. Erec Stebbins

https://www.biorxiv.org/content/10.1101/2020.06.04.134106v1

Whole Cell Phenotypic Screening Of MMV Pathogen Box identifies Specific Inhibitors of Plasmodium falciparum merozoite maturation and egress

Alok Tanala Patra, Tejashri Bhimashankar Hingmire, Meenakshi Belekar, Aoli Xiong, Gowtham Subramanian, Zbynek Bozdech, Peter Preiser, Dhanasekaran Shanmugam, Rajesh Chandramohanadas

https://www.biorxiv.org/content/10.1101/772434v1

Reevaluation of the Toxoplasma gondii and Neospora caninum genomes reveals misassembly, karyotype differences and chromosomal rearrangements

Luisa Berna, Pablo Marquez, Andrés Cabrera, Gonzalo Greif, María E. Francia, Carlos Robello

https://www.biorxiv.org/content/10.1101/2020.05.22.111195v1

Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes

Joana Faria, Vanessa Luzak, Laura S.M. Müller, Benedikt G. Brink, Sebastian Hutchinson, Lucy Glover, David Horn, T. Nicolai Siegel

https://www.biorxiv.org/content/10.1101/2020.01.27.921452v1

Single cell sequencing of the small and AT-skewed genome of malaria parasites

Shiwei Liu, Adam C. Huckaby, Audrey C. Brown, Christopher C. Moore, Ian Burbulis, Michael J. McConnell, Jennifer L. Güler

https://www.biorxiv.org/content/10.1101/2020.02.21.960039v2

Bulk Segregant Approaches to Nutritional Genomics in Plasmodium falciparum

Sudhir Kumar, Xue Li, Marina McDew-White, Ann Reyes, Abeer Sayeed, Meseret T. Haile, Spencer Y. Kennedy, Nelly Camargo, Lisa A. Checkley, Katelyn M. Vendrely, Katrina A. Button-Simons, Ian H. Cheeseman, Stefan H. Kappe, François Nosten, Michael T. Ferdig, Ashley M. Vaughan, Tim J. C. Anderson

https://www.biorxiv.org/content/10.1101/2020.09.12.294736v1

Establishment of quantitative RNAi-based forward genetics in Entamoeba histolytica and identification of genes required for growth

Akhila Bettadapur, Samuel S. Hunter, Charles G. Barbieri, Matthew L. Settles, Katherine S. Ralston

https://www.biorxiv.org/content/10.1101/2020.05.28.121780v1

Fussing about fission: defining variety among mainstream and exotic apicomplexan cell division modes

Marc-Jan Gubbels, Caroline D. Keroack, Sriveny Dangoudoubiyam, Hanna L. Worliczek, Aditya S. Paul, Ciara Bauwens, Brendan Elsworth, Klemens Engelberg, Daniel K. Howe, Isabelle Coppens, Manoj T. Duraisingh

https://www.biorxiv.org/content/10.1101/2020.04.23.056333v2

Unconventional kinetochore kinases KKT2 and KKT3 have a unique zinc finger that promotes their kinetochore localization

Gabriele Marcianò, Olga O. Nerusheva, Midori Ishii, Bungo Akiyoshi

https://www.biorxiv.org/content/10.1101/2019.12.13.875419v1

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds

Madeline G. Dans, Greta E. Weiss, Danny W. Wilson, Brad E. Sleebs, Brendan S. Crabb, Tania F. de Koning-Ward, Paul R. Gilson

https://www.biorxiv.org/content/10.1101/768648v1

18S rDNA Sequence-Structure Phylogeny of the Trypanosomatida (Kinetoplastea, Euglenozoa) with Special Reference on Trypanosoma

Alyssa R. Borges, Markus Engstler, Matthias Wolf

https://www.biorxiv.org/content/10.1101/2020.08.04.235945v1

A long non-coding RNA controls parasite differentiation in African trypanosomes

F. Guegan, F. Bento, D. Neves, M. Sequeira, C. Notredame, L.M. Figueiredo

https://www.biorxiv.org/content/10.1101/2020.05.03.074625v1

Potentially zoonotic gastrointestinal nematodes co-infecting free ranging non-human primates in Kenyan urban centres

Peris Mbuthia, Edwin Murungi, Vincent Owino, Mercy Akinyi, Gillian Eastwood, Richard Nyamota, Isaac Lekolool, Maamun Jeneby

https://www.biorxiv.org/content/10.1101/2020.08.19.254714v2

Dually localized proteins found in both the apicoplast and mitochondrion utilize the Golgi-dependent pathway for apicoplast targeting in Toxoplasma gondii

Aparna Prasad, Pragati Mastud, Swati Patankar

https://www.biorxiv.org/content/10.1101/2020.03.25.007476v1

Toxoplasma ferlin1 is a versatile and dynamic mediator of microneme trafficking and secretion

Daniel N.A. Tagoe, Allison A. Drozda, Isabelle Coppens, Bradley I. Coleman, Marc-Jan Gubbels

https://www.biorxiv.org/content/10.1101/2020.04.27.063628v1

Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages

Leen Vanheer, Björn F.C. Kafsack

https://www.biorxiv.org/content/10.1101/694422v1

A Genome-wide CRISPR-Cas9 Screen Identifies Host Factors Essential for Optimal Plasmodium Liver Stage Development

Kamalakannan Vijayan, Nadia Arang, Ling Wei, Robert Morrison, Rechel Geiger, K. Rachael Parks, Adam J Lewis, Fred D Mast, Alyse N Douglass, Heather S Kain, John D Aitchison, Jarrod S Johnson, Alan Aderem, Alexis Kaushansky

https://www.biorxiv.org/content/10.1101/2020.08.31.275867v1

Loss of the conserved Alveolate kinase MAPK2 decouples Toxoplasma cell growth from the cell cycle

Xiaoyu Hu, William J. O’Shaughnessy, Tsebaot G. Beraki, Michael L. Reese

https://www.biorxiv.org/content/10.1101/2020.05.13.095091v2

High speed, three-dimensional imaging reveals chemotactic behavior specific to human-infective Leishmania parasites

Rachel C. Findlay, Mohamed Osman, Kirsten A. Spence, Paul M. Kaye, Pegine B. Walrad, Laurence G. Wilson

https://www.biorxiv.org/content/10.1101/2020.07.30.220541v1

 

Posted on: 23rd September 2020 , updated on: 26th September 2020

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