I’m a neurophysiologist working on neocortical and hypothalamic circuitry with patch clamp in slices and Ca++ imaging in vivo.
Opposing influence of top-down and bottom-up input on different types of excitatory layer 2/3 neurons in mouse visual cortex
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07 April 2020
Mahesh Karnani
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Strong preference for autaptic self-connectivity of neocortical PV interneurons entrains them to γ-oscillations
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20 December 2018
Mahesh Karnani
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon
AND
High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins
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22 July 2018
Mahesh Karnani
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Cerebellar contribution to preparatory activity in motor neocortex
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17 July 2018
Mahesh Karnani
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex
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31 May 2018
Mahesh Karnani
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)