I started my career in the stem cell field in 2007. I studied for a master degree at the National Institute of Health and Medical Research (INSERM – France – Lyon) and was awarded the PhD degree in the same institute (on the 16/12/2013). I received further research training as a Postdoctoral fellow until June 2014.
In July 2014, I began a second Postdoctoral training in the Embryology unit leaded by Prof. Patrick Tam. Working in his group is a wonderful opportunity for me as my knowledge is always at the forefront of the field.
My interests are focused on the early mammalian embryo development. In the mouse model, I use embryonic stem cell (ESC) and Epiblast stem cell (EpiSC) while using induced Pluripotent Stem Cells (iPSC) to understand human biology. My aim is to discover new molecular regulations that are governing cell fate decision during the establishment of primitive germ layers.
Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization
Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development
Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation
Genetically regulated human NODAL splice variants are differentially post-transcriptionally processed and functionally distinct
Lineage tracing axial progenitors using Nkx1.2CreERT2 mice defines their trunk and tail contributions
An Epiblast Stem Cell derived multipotent progenitor population for axial extension