I am a cell biologist currently working as a postdoctoral researcher at Institut curie, Paris with Dr. Christophe Lamaze. My research interest lies in understanding how migrating cells read and interpret mechano-chemical stimuli.
In my Ph.D. work with Dr. Nagaraj Balasubramanian (IISER Pune, India), I discovered a novel regulation by cell-matrix adhesion on Golgi organization and function in anchorage-dependent mammalian cells (Singh et al., JCS, 2018). Findings from my thesis work could have implications in cell-matrix biology research in disease conditions and also a role in established mitotic-Golgi fragmentation pathway.
Long range mutual activation establishes Rho and Rac polarity during cell migration
Vibha SINGH
Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration
Vibha SINGH
Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly
Vibha SINGH
The actin cortex acts as a mechanical memory of morphology in confined migrating cells
Prasanna Padmanaban, Vibha SINGH
Actin dynamics sustains spatial gradients of membrane tension in adherent cells
Vibha SINGH
Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity
Vibha SINGH
Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility
Vibha SINGH
Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
Vibha SINGH
GIV•Kindlin interaction is required for Kindlin-Mediated Integrin Recognition and Activation
Vibha SINGH
WASP restricts active Rac to maintain cells’ front-rear polarisation
Vibha SINGH
Mechanical Stretch Kills Transformed Cancer Cells
Vibha SINGH