Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes
Joao Gabriel, Marcus Oliveira
4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity
Hannah Pletcher
A potential anti-amyloidogenic therapy for type 2 diabetes based on the QBP1 peptide
Joao Gabriel, Marcus Oliveira
Oxidative stress triggers RNAPII arrest through PARylation and DNA damage
Élise Jeanne Pouponnot, Pierre Caron
Human Assembloid Model of Emergent Neurotropic Enteroviruses
Mitchell Sarmie
Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching
Cyntia Alves Conceição, Marcus Oliveira
Classical enhancers couple cis-regulatory logic with transcriptional condensates and 3D genome architecture
Siddharth Singh
Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models
Dina Kabbara
A thirty-year trend of increasing clinical orientation at the National Institutes of Health
AND
Prediction of transformative breakthroughs in biomedical research
Jonathan Townson
Keystone Symposium on Stem Cell Models in Embryology 2026
The Keystone Symposium on Stem Cell Models in Embryology, 2026, was organised by Jun Wu (UT Southwestern), Jianping Fu (University of Michigan) and Miki Ebisuya (TU Dresden) and held at Asilomar Conference Grounds in California (US). The meeting discussed recent advances made in establishing stem-cell-based embryo models, what fundamental insights into developmental processes have been gleaned from them, as well as how they are beginning to be applied more widely. This prelist contains preprints by presenters at the talk and poster sessions at the conference, which our Reviews Editor in attendance spotted. Please do reach out to preLights@biologists.com if you notice any that we’ve missed.
| List by | Ingrid Tsang |
Cell-intrinsic compliance mechanism enables release of tensile stress to prevent tissue rupture
Ruoheng Li
'Preprints by preLighters': Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro
Reinier Prosee, Teodora Piskova