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Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Selected by 06 January 2026

Leonie Brüne

Molecular Biology

Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling

Haley N. Bridge, Chase L. Radziej, Amy M. Weeks

Selected by 31 December 2025

Zhang-He Goh

Biochemistry

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S.C. Gravett, et al.

Selected by 31 December 2025

Vibha SINGH

Cell Biology

PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Selected by 29 December 2025

Vibha SINGH

Cell Biology

Junctional Heterogeneity Shapes Epithelial Morphospace

Anubhav Prakash, Raman Kaushik, Nishant Singh, et al.

Selected by 25 December 2025

Bhaval Parmar

Developmental Biology

Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation

Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Mauricio S. Baptista, et al.

Selected by 19 December 2025

Rickson Ribeiro, Marcus Oliveira

Biochemistry
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See all preLight posts (1732)

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Latest spotLight

spotLights is an interview series dedicated to highlighting exciting new preprints in the biological sciences and the early-career researchers driving the work.

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Latest news

From preLighter to Executive Editor: How Samantha Seah helps students find their voice in science

In this interview, we hear from Samantha Seah, a former preLighter who will soon step into the role of Executive Editor at the Journal of Emerging Investigators. Here, Samantha traces JEI’s origins, explains how student projects are reviewed and supported, describes recent expansions like eiRxiv and teacher resources, and shares…

Posted on 10 December 2025

Preprints by preLighters: Hala Taha

Every research paper carries a story—one that rarely makes it into the methods or the discussion section. Mine begins in a small parasitology lab in Sudan, on the last day before the war forced me to flee. That morning, a photo was taken of me and a colleague as we…

Posted on 24 November 2025

preLighting with a little help from AI

Written by: Reinier Prosée, preLights Community Manager Note: this post got a little help from Microsoft Copilot to keep things clear and to-the-point. Writing is perhaps more an art than a science, something I realised while co-moderating a creative workshop on science communication earlier this year. This is not to…

Posted on 17 November 2025

Recent preLists

November in preprints – DevBio & Stem cell biology

preLighters with expertise across developmental and stem cell biology have nominated a few developmental and stem cell biology (and related) preprints posted in November they’re excited about and explain in a single paragraph why. Concise preprint highlights, prepared by the preLighter community – a quick way to spot upcoming trends, new methods and fresh ideas.

 



List by Aline Grata et al.

October in preprints – DevBio & Stem cell biology

Each month, preLighters with expertise across developmental and stem cell biology nominate a few recent developmental and stem cell biology (and related) preprints they’re excited about and explain in a single paragraph why. Short, snappy picks from working scientists — a quick way to spot fresh ideas, bold methods and papers worth reading in full. These preprints can all be found in the October preprint list published on the Node.

 



List by Deevitha Balasubramanian et al.

October in preprints – Cell biology edition

Different preLighters, with expertise across cell biology, have worked together to create this preprint reading list for researchers with an interest in cell biology. This month, most picks fall under (1) Cell organelles and organisation, followed by (2) Mechanosignaling and mechanotransduction, (3) Cell cycle and division and (4) Cell migration

 



List by Matthew Davies et al.

September in preprints – Cell biology edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading list. This month, categories include: (1) Cell organelles and organisation, (2) Cell signalling and mechanosensing, (3) Cell metabolism, (4) Cell cycle and division, (5) Cell migration

 



List by Sristilekha Nath et al.
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