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The effect of absent blood flow on the zebrafish cerebral and trunk vasculature

Elisabeth Kugler, Ryan Snodgrass, George Bowley, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced hypertension and kidney injury

Catalina Sierra-Ramos, Silvia Velazquez-Garcia, Ayse G. Keskus, et al.

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair

Jaymin J. Kathiriya, Chaoqun Wang, Alexis Brumwell, et al.

Conservation of the Toxoplasma conoid proteome in Plasmodium reveals a cryptic conoid feature that differentiates between blood- and vector-stage zoites

Ludek Koreny, Mohammad Zeeshan, Konstantin Barylyuk, et al.

Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries

Arman Namvar, Adam J. Blanch, Matthew W. Dixon, et al.

Expansion Microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid

Eloïse Bertiaux, Aurélia C Balestra, Lorène Bournonville, et al.

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.

Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum

Thomas C. A. Blake, Silvia Haase, Jake Baum

Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes

Radoslaw P. Kozak, Karina Mondragon-Shem, Christopher Williams, et al.

Discussion

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei

Simona Amodeo, Ana Kalichava, Albert Fradera-Sola, et al.