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Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Wei Zheng, Igor Siwanowicz, et al.

Selected by 12 December 2025

Muhammed Sinan Malik

Neuroscience

Microbial Feast or Famine: dietary carbohydrate composition and gut microbiota metabolic function

Blake Dirks, Alex E. Mohr, Karen D. Corbin, et al.

Selected by 11 December 2025

Jasmine Talevi

Clinical Trials

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Selected by 09 December 2025

Inês Caiado

Immunology

Vitamin B12 supports skeletal muscle oxidative phosphorylation capacity in male mice

Luisa F. Castillo, Katarina E. Heyden, Abigail R. Williamson, et al.

Selected by 08 December 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry

Dosage-sensitive RBFOX2 autoregulation promotes cardiomyocyte differentiation by maturing the transcriptome

Mengmeng Huang, Feria A. Ladha, Yunxia Wang, et al.

Selected by 06 December 2025

Theodora Stougiannou

Developmental Biology

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Selected by 02 December 2025

Siddharth Singh

Evolutionary Biology
See all preLight posts (1725)

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See all preLight posts (1725)

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Latest spotLight

spotLights is an interview series dedicated to highlighting exciting new preprints in the biological sciences and the early-career researchers driving the work.

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Latest news

From preLighter to Executive Editor: How Samantha Seah helps students find their voice in science

In this interview, we hear from Samantha Seah, a former preLighter who will soon step into the role of Executive Editor at the Journal of Emerging Investigators. Here, Samantha traces JEI’s origins, explains how student projects are reviewed and supported, describes recent expansions like eiRxiv and teacher resources, and shares…

Posted on 10 December 2025

Preprints by preLighters: Hala Taha

Every research paper carries a story—one that rarely makes it into the methods or the discussion section. Mine begins in a small parasitology lab in Sudan, on the last day before the war forced me to flee. That morning, a photo was taken of me and a colleague as we…

Posted on 24 November 2025

preLighting with a little help from AI

Written by: Reinier Prosée, preLights Community Manager Note: this post got a little help from Microsoft Copilot to keep things clear and to-the-point. Writing is perhaps more an art than a science, something I realised while co-moderating a creative workshop on science communication earlier this year. This is not to…

Posted on 17 November 2025

Recent preLists

November in preprints – DevBio & Stem cell biology

preLighters with expertise across developmental and stem cell biology have nominated a few developmental and stem cell biology (and related) preprints posted in November they’re excited about and explain in a single paragraph why. Concise preprint highlights, prepared by the preLighter community – a quick way to spot upcoming trends, new methods and fresh ideas.

 



List by Aline Grata et al.

October in preprints – DevBio & Stem cell biology

Each month, preLighters with expertise across developmental and stem cell biology nominate a few recent developmental and stem cell biology (and related) preprints they’re excited about and explain in a single paragraph why. Short, snappy picks from working scientists — a quick way to spot fresh ideas, bold methods and papers worth reading in full. These preprints can all be found in the October preprint list published on the Node.

 



List by Deevitha Balasubramanian et al.

October in preprints – Cell biology edition

Different preLighters, with expertise across cell biology, have worked together to create this preprint reading list for researchers with an interest in cell biology. This month, most picks fall under (1) Cell organelles and organisation, followed by (2) Mechanosignaling and mechanotransduction, (3) Cell cycle and division and (4) Cell migration

 



List by Matthew Davies et al.

September in preprints – Cell biology edition

A group of preLighters, with expertise in different areas of cell biology, have worked together to create this preprint reading list. This month, categories include: (1) Cell organelles and organisation, (2) Cell signalling and mechanosensing, (3) Cell metabolism, (4) Cell cycle and division, (5) Cell migration

 



List by Sristilekha Nath et al.
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