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Vinculin mediated axon growth requires interaction with actin but not talin

Pranay Mandal, Vivek Belapurkar, Deepak Nair, et al.

Cancer associated talin point mutations disorganise cell adhesion and migration

Latifeh Azizi, Alana R. Cowell, Vasyl V. Mykuliak, et al.

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

An early cell shape transition drives evolutionary expansion of the human forebrain

Silvia Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena Sutcliffe, et al.

A flagellate-to-amoeboid switch in the closest living relatives of animals

Thibaut Brunet, Marvin Albert, William Roman, et al.

Upregulation and cell specificity of C₄ genes are derived from ancestral C₃ gene regulatory networks

Pallavi Singh, Sean R. Stevenson, Ivan Reyna-Llorens, et al.

Discussion

Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced hypertension and kidney injury

Catalina Sierra-Ramos, Silvia Velazquez-Garcia, Ayse G. Keskus, et al.

The First Mitotic Division of the Human Embryo is Highly Error-prone

Emma Ford, Cerys E. Currie, Deborah M. Taylor, et al.

Discussion

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Discussion

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Discussion

Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, et al.