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ARID1A regulates R-loop associated DNA replication stress

Shuhe Tsai, Emily Yun-Chia Chang, Louis-Alexandre Fournier, et al.

A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2

Aurora Kraus, Elisa Casadei, Mar Huertas, et al.

Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring

Filippo Mirabella, Genni Desiato, Sara Mancinelli, et al.

SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism

Daisy Castillo-Guzman, Stella R. Hartono, Lionel A. Sanz, et al.

Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors

Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, et al.

Discussion

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Jean Farup, Jesper Just, Frank de Paoli, et al.

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

Jerome Avellaneda, Clement Rodier, Fabrice Daian, et al.

Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence

Man Shun Fu, Livia C. Liporagi-Lopes, Samuel R. dos Santos Júnior, et al.

Apico-basal cell compression regulates Lamin A/C levels in Epithelial tissues

K Venkatesan Iyer, Natalie A. Dye, Suzanne Eaton, et al.

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

Hui Huang, Quan Zhu, Adam Jussila, et al.