Expansion microscopy at one nanometer resolution
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24 November 2022
Nadja Hümpfer
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease
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19 August 2021
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner
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07 July 2021
Emma Wilson
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly
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05 June 2021
Joanna Zell
![Biochemistry Biochemistry](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biochemistry.png)
Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons
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26 May 2021
Emma Wilson
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation
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20 May 2021
Eric McGregor
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Selectivity of Protein Interactions along the Aggregation Pathway of α-Synuclein
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15 April 2021
Utrecht Protein Folding and Assembly
![Biochemistry Biochemistry](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biochemistry.png)
Brain deletion of Serf2 shifts amyloid conformation in a mouse model
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06 April 2021
Utrecht Protein Folding and Assembly
![Molecular Biology Molecular Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/molecular-biology.png)
Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates
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11 March 2021
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice
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21 August 2020
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates
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18 December 2019
Jessica Xie
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain
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20 September 2019
Tessa Sinnige
![Biophysics Biophysics](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biophysics.png)