LINC complex alterations are a hallmark of sporadic and familial ALS/FTD
Selected by
03 June 2024
Megane Rayer et al.
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis
Selected by
16 April 2024
Julio Molina Pineda
![Genomics Genomics](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/genomics.png)
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4
Selected by
22 October 2023
Aniruddha Das
![Biochemistry Biochemistry](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biochemistry.png)
VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity
Selected by
10 February 2023
Kritika Mehta
![Biochemistry Biochemistry](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biochemistry.png)
Motion of single molecular tethers reveals dynamic subdomains at ER-mitochondria contact sites
Selected by
06 November 2022
Holly Smith
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis
Selected by
09 April 2021
Utrecht Protein Folding and Assembly
![Biochemistry Biochemistry](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/biochemistry.png)
Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates
Selected by
11 March 2021
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Selected by
05 February 2021
Sree Rama Chaitanya, Giuseppina D'Alessandro
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)
Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
Selected by
10 September 2020
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
Selected by
01 August 2020
Kristina Kuhbandner
![Neuroscience Neuroscience](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/neuroscience.png)
FUS gene is dual-coding with both proteins united in FUS-mediated toxicity
Selected by
12 May 2020
Madhuja Samaddar
![Molecular Biology Molecular Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/molecular-biology.png)
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
Selected by
30 August 2019
Madhuja Samaddar
![Cell Biology Cell Biology](https://prelights.biologists.com/wp-content/themes/thecobpph/assets/images/categories/transparent-no-type/cell-biology.png)