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Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

Maggy Yu Hei Lau, Sana Gadiwalla , Susan Jones, et al.

Selected by Ana Dorrego-Rivas, Emily Winson-Bushby

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by Benjamin Dominik Maier

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by Audrey Noireterre

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.

Selected by Benjamin Dominik Maier et al.

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

Selected by Hellen Costa, Marcus Oliveira

Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

Kaitlin N Allen, Julia María Torres-Velarde, Juan Manuel Vazquez, et al.

Selected by Sarah Young-Veenstra

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by Jessica Chevallier, Pierre Caron

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Kenrick A. Waite, Gabrielle Vontz, Stella Y. Lee, et al.

Selected by Aniruddha Das

A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks

Song Feng, James A. Sanford, Thomas Weber, et al.

Selected by Benjamin Dominik Maier

H₂O₂ sulfenylates CHE linking local infection to establishment of systemic acquired resistance

Lijun Cao, Heejin Yoo, Tianyuan Chen, et al.

Selected by Marc Somssich

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains

Selected by Benjamin Dominik Maier, Anna Foix Romero

VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis

Fatima Rizvi, Yu-Ri Lee, Ricardo Diaz-Aragon, et al.

Selected by Organogenesis and Cancer Program