The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to brca1-independent PARP inhibitor sensitivity
Selected by
14 November 2023
Audrey Noireterre
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
05 June 2023
Pierre Caron
EXO1-mediated DNA repair by single-strand annealing is essential for brca1-deficient cells
Selected by
15 May 2023
Jennifer Ann Black
brca1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis
Selected by
09 March 2023
Pierre Caron
Nuclear myosin VI maintains replication fork stability
Selected by
13 December 2022
Pierre Caron
Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation
Selected by
20 June 2022
Pierre Caron
Saturation variant interpretation using CRISPR prime editing
Selected by
20 October 2021
Jeffrey Calhoun
Two redundant ubiquitin-dependent pathways of brca1 localization to DNA damage sites
Selected by
10 August 2021
Giuseppina D'Alessandro
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Selected by
05 February 2021
Sree Rama Chaitanya, Giuseppina D'Alessandro
EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
Selected by
05 January 2021
Sree Rama Chaitanya
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
Selected by
31 December 2020
Giuseppina D'Alessandro
Aberrant replication licensing drives Copy Number Gains across species
Selected by
12 October 2020
Yasmin Lau