Search results

ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion

Daniel A. Reed, Anna E. Howell, Nadia Kuepper, et al.

Selected by 27 November 2025

Sharvari Pitke

TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling

Janik Engelmann, Jennifer Zarrer, Max Schmerder, et al.

Selected by 14 October 2025

André Luiz Amorim Costa, Marcus Oliveira

Discussion

Tumor-infiltrating CD27^-IgD^- regulatory B cells suppress cytotoxic CD8⁺T cell responses in renal cell carcinoma

Zara Baig, Isabella Withnell, Joseph C.F. Ng, et al.

Selected by 12 August 2025

Charis Qi

Tumoral CD24 tunes platelet binding and pro-metastatic functions

Vincent Mittelheisser, Cristina Liboni, Clarisse Mouriaux, et al.

Selected by 16 June 2025

Harvey Roweth

Swirling motion of breast cancer cells radially aligns collagen fibers to enable collective invasion

Aashrith Saraswathibhatla, Md Foysal Rabbi, Sushama Varma, et al.

Selected by 10 June 2025

Sharvari Pitke

An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer

Wenyan Xie, Xin Yu, Qingxin Yang, et al.

Selected by 20 May 2025

Roberto Amadio

Discussion

Optogenetic stimulation of Lbc GEF-mediated Rho activity dynamics promotes cell invasion

Jessica Wagner, Konstantina Feller, Nicole Schrenke, et al.

Selected by 25 April 2025

Vibha SINGH

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Marco De Donatis, et al.

Selected by 07 October 2024

Simon Cleary

Actin polymerization drives lumen formation in a human epiblast model

Dhiraj Indana, Andrei Zakharov, Youngbin Lim, et al.

Selected by 05 April 2024

Megane Rayer, Rivka Shapiro

Inferring protein from mRNA concentrations using convolutional neural networks

Patrick Maximilian Schwehn, Pascal Falter-Braun

Selected by 20 December 2023

Benjamin Dominik Maier

Mechano-dependent sorbitol accumulation supports biomolecular condensate

Stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.

Selected by 07 September 2023

Teodora Piskova

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Discussion