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A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.

Selected by 13 February 2023

Silvia Becca

Bioengineering

Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis

Hélène Vignes, Christina Vagena-Pantoula, Mangal Prakash, et al.

Selected by 25 August 2021

Julia Grzymkowski

Developmental Biology

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Selected by 13 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Selected by 18 June 2020

Zhang-He Goh

Pharmacology and Toxicology

Depression of heart rate in fish at critically high temperatures is due to atrioventricular block

Jaakko Haverinen, Matti Vornanen

Selected by 26 March 2020

James Marchant

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