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Programmable pathway profiles reveal signaling principles of TGF-β superfamily receptors

Bo Gu, James M Linton, Brice Graham Hendrickson, et al.

Discussion

Disrupting a Convergent Acetylation Circuit Collapses Leukemic Identity Across AML Subtypes

Anagha Deshpande, Cho-Ying Chiang, Marlenne Perales, et al.

Discussion

Epigenome editing of human hematopoietic stem cells enables sustained and reversible thrombosis prevention

Tianyi Ye, Wanying Xu, Maria N. Barrachina, et al.

Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis

William N. Colgan, Luke W. Koblan, JoAnne Villagrana, et al.

Discussion

Combinatorial and Inducible crispra/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Classical enhancers couple cis-regulatory logic with transcriptional condensates and 3D genome architecture

Ville Tiusanen, Divyesh Patel, Jihan Xia, et al.

Discussion

A drought stress-induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula)

Sijia Liu, Siamsa M. Doyle, Kathryn M. Robinson, et al.

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

High-throughput single-cell crispri screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Discussion

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors

Koji Matsuda, Chung-Han Wang, Atsushi Toyoda, et al.

Discussion