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High-throughput single-cell crispri screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Neuroscience

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors

Koji Matsuda, Chung-Han Wang, Atsushi Toyoda, et al.

Selected by 27 October 2025

Muhammed Sinan Malik

Neuroscience

Condensation of Sidekick at tricellular junctions organizes mechanical forces for cell-cell adhesion remodeling

Hiroyuki Uechi, Daxiao Sun, Yuki Saeki, et al.

Selected by 17 October 2025

Fatima Rafiq

Biophysics

Wide-ranging behavioral dysfunction in two mouse models of pathological human variants in the GRIK2 kainate receptor gene

Brynna T. Webb, Hieu Trinh, Emily A. Breach, et al.

Selected by 18 August 2025

Pushpinder Singh

Neuroscience

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Neuroscience

IMMClock reveals immune aging and T cell function at single-cell resolution

Yael Gurevich Schmidt, Di Wu, Sanna Madan, et al.

Selected by 19 January 2025

Jessica Chevallier

Bioinformatics

Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods

Constantin Ahlmann-Eltze, Wolfgang Huber, Simon Anders

Selected by 11 November 2024

Benjamin Dominik Maier

Bioinformatics

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

Alice E Mortimer, Adam J Reid, Raman M Das

Selected by 15 October 2024

Vibha SINGH

Cell Biology

Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Emily N. P. Prowse, Abdullah R. Chaudhary, David Sharon, et al.

Selected by 21 August 2024

Abhishek Poddar

Cell Biology

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Selected by 24 June 2024

Girish Kale, Jennifer Ann Black

Developmental Biology

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

Kate E. McCluskey, Katherine M. Stovell, Karen Law, et al.

Selected by 10 June 2024

Rachel Mckeown

Neuroscience

Lipid-Based Transfection of Zebrafish Embryos: A Robust Protocol for Nucleic Acid Delivery

Aslihan Terzi, Tiger Liao, Adrian Jacobo

Selected by 09 May 2024

Roberto Rodríguez-Morales

Genetics