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IMMClock reveals immune aging and T cell function at single-cell resolution

Yael Gurevich Schmidt, Di Wu, Sanna Madan, et al.

Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods

Constantin Ahlmann-Eltze, Wolfgang Huber, Simon Anders

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

Alice E Mortimer, Adam J Reid, Raman M Das

Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Emily N. P. Prowse, Abdullah R. Chaudhary, David Sharon, et al.

Discussion

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

Kate E. McCluskey, Katherine M. Stovell, Karen Law, et al.

Lipid-Based Transfection of Zebrafish Embryos: A Robust Protocol for Nucleic Acid Delivery

Aslihan Terzi, Tiger Liao, Adrian Jacobo

Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

Martina Begnis, Julien Duc, Sandra Offner, et al.

A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

Luca Livraghi, Joseph J. Hanly, Elizabeth Evans, et al.

AND

The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Richard A. Fandino, Noah K. Brady, Martik Chatterjee, et al.

AND

A micro-RNA drives a 100-million-year adaptive evolution of melanic patterns in butterflies and moths

Shen Tian, Tirtha Das Banerjee, Jocelyn Liang Qi Wee, et al.

The genetic basis of novel trait gain in walking fish

Amy L Herbert, Corey AH Allard, Matthew J McCoy, et al.

Discussion

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, et al.

Discussion

Modeling transcriptional profiles of gene perturbation with a deep neural network

Wenke Liu, Xuya Wang, D R Mani, et al.

Discussion