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Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of dna double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by Pierre Caron

EXO1-mediated dna repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by Jennifer Ann Black

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Selected by Fiona Macleod

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Selected by Saanjbati Adhikari

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Selected by Roberto Amadio

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous dna synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by Pierre Caron

Single-strand mismatch and damage patterns revealed by single-molecule dna sequencing

Mei Hong Liu, Benjamin Costa, Una Choi, et al.

Selected by Kerryn Elliott

Nuclear myosin VI maintains replication fork stability

Jie Shi, Kristine Hauschulte, Ivan Mikicic, et al.

Selected by Pierre Caron

Gigaxonin is required for intermediate filament transport

Bhuvanasundar Renganathan, James P Zewe, Yuan Cheng, et al.

Selected by Suganya Sivagurunathan

Tissue confinement regulates cell growth and size in epithelia

John Devany, Martin J. Falk, Liam J. Holt, et al.

Selected by Nicolaes Hyun-Kee Min

Sub-lethal apoptotic stress enables mtdna release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Selected by Roberto Amadio

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, et al.

Selected by Pierre Caron