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Combinatorial and Inducible CRISPRa/i Enables Canalized hipsc Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Synthetic Biology

Human Assembloid Model of Emergent Neurotropic Enteroviruses

Christine E. Peters, Jimena Andersen, Min-Yin Li, et al.

Selected by 01 April 2026

Mitchell Sarmie

Microbiology

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Selected by 11 February 2026

Isabel Paine

Neuroscience

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Selected by 14 November 2025

Manuel Lessi

Neuroscience

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation

Marika Oksanen, Francesca Mastropasqua, Krystyna Mazan-Mamczarz, et al.

Selected by 24 June 2025

Candy Rutihinda et al.

Molecular Biology

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Neuroscience

Succinate Dehydrogenase loss causes cascading metabolic effects that impair pyrimidine biosynthesis

Madeleine L. Hart, Kristian Davidsen, Serwah Danquah, et al.

Selected by 26 May 2025

Hannah Pletcher

Cancer Biology

Heart Scar-In-A-Dish: Tissue Culture Platform to Study Myocardial Infarct Healing In Vitro

MJ Potter, JD Heywood, SJ Coeyman, et al.

Selected by 28 April 2025

Theodora Stougiannou

Bioengineering

TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stability

Charlie Moffatt, Ankita Arora, Katherine F. Vaeth, et al.

Selected by 10 April 2025

Felipe Del Valle Batalla

Cell Biology

Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates

Karen A Lindquist, Jennifer Mecklenburg, Anahit H. Hovhannisyan, et al.

Selected by 04 December 2024

Vanessa Ehlers

Neuroscience

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Biochemistry

Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions

Yang Yang, Luis A. Valencia, Chih-Hao Lu, et al.

Selected by 07 August 2024

Barbora Knotkova

Cell Biology