You searched for ipsc

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

Selected by Matthew Davies

CRISPR screens in ipsc-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Selected by Kritika Mehta

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Jin Hao, et al.

Selected by Monica Tambalo

Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters

Adam M. Zahm, William S. Owens, Samuel R. Himes, et al.

Selected by Jessica L. Teo

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by Pierre Caron

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

Selected by Benjamin Dominik Maier

A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.

Selected by Silvia Becca

Young transposable elements rewired gene regulatory networks in human and chimpanzee hippocampal intermediate progenitors

Sruti Patoori, Samantha Barnada, Marco Trizzino

Selected by Julia Grzymkowski

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

Guillermo Martínez-Ara, Núria Taberner, Mami Takayama, et al.

Selected by Monica Tambalo

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

Benjamin J. Tuck, Taxiarchis Katsinelos, Lauren V. C. Miller, et al.

Selected by Emma Wilson

YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.

Selected by Srivatsava Viswanadha

Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons

Abeer Dagra, Douglas R. Miller, Fatemeh Shaerzadeh, et al.