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4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, Maria Miranda, Fangcong Dong, et al.

Discussion

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Discussion

Resilience to cardiac aging in Greenland shark Somniosus microcephalus

Elena Chiavacci, Kirstine Fleng Steffensen, Pierre Delaroche, et al.

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Discussion

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Discussion

Vitamin B12 supports skeletal muscle oxidative phosphorylation capacity in male mice

Luisa F. Castillo, Katarina E. Heyden, Abigail R. Williamson, et al.

Discussion

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells

Rita Berkachy, Vishwas Mishra, Priyanka Biswas, et al.

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Gut microbial composition modulates food-specific CD4⁺ T cells in food allergy

Alexa R Weingarden, Flannery S Dahlberg, Caroline N Broude, et al.

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, et al.

Maturation of the glymphatic system confers innate resistance of the brain to Zika virus infection

Jhulimar Guilherme Doerl, Emanuelly Karine Campos Chaves, Vivian Antonielly Becker dos Santos, et al.